Supplementary Figure 6: HSD does not increase Il17a mRNA levels or TH17 cells in both brain and meninges.
From: Dietary salt promotes neurovascular and cognitive dysfunction through a gut-initiated TH17 response
A: HSD does not alter number and B: frequency of T helper and TH17 cells in brain and meninges. Brain T helper: p = 0.1671 vs ND and p = 0.9157 vs ND; Meningeal T helper: p = 0.3882 vs ND and p = 0.5669 vs ND; Brain TH17 cells: p = 0.8709 vs ND and p = 0.6491 vs ND; Meningeal TH17 cells: p = 0.7677 vs ND and p = 0.3192 vs ND; n = 5/group, 2 mice/samples (unpaired t-test, two-tailed). C: IL-17 mRNA levels are not increased in the brain or meninges of mice fed a HSD. Meninges: p = 0.6465 vs ND; ND/HSD n = 4/5 mice group (unpaired t-test, two-tailed). Data are expressed as mean ± SEM.
