Supplementary Figure 12: Dynamics of chromatin accessibility within distinct cell groups.

a Number of reads in peaks per developmental time point for a specific nuclei cluster. b Number of nuclei per time point for a specific nuclei cluster. For analysis of dynamics only cell clusters with > 3 stages with > 50 nuclei and > 250,000 reads in peaks were considered. c Overview of dynamic elements identified per cell cluster (see methods) d–g K-means clustering and motif enrichment analysis for nuclei clusters with > 200 dynamic genomic elements. Statistical test for motif enrichment: hypergeometric test. P-values were not corrected for multiple testing50. (e: embryonic; RG: Radial glia; EX: Excitatory neuron; IN: Inhibitory neuron; EMP: Erythromyeloid progenitor cell; AC: Astrocyte).