Supplementary Figure 4: snATAC-seq data sets are robust and reproducible. | Nature Neuroscience

Supplementary Figure 4: snATAC-seq data sets are robust and reproducible.

From: Single-nucleus analysis of accessible chromatin in developing mouse forebrain reveals cell-type-specific transcriptional regulation

Supplementary Figure 4: snATAC-seq data sets are robust and reproducible.

Pearson correlation of chromatin accessibility profiles from two independent experiments derived from bulk ATAC-seq (left column) and from aggregate snATAC-seq after aggregating single nuclei profiles (middle column) is shown in each plot. In the right column the correlation between bulk ATAC-seq and aggregate snATAC-seq are displayed for the experiment on the first set of forebrain tissues. Data are displayed from forebrain tissues from following time points: a. E11.5, b. E12.5, c. E13.5, d. E14.5, e. E15.5, f. E16.5, g. P0, and h. P56. For bulk ATAC-seq data generated by the ENCODE consortium were processed (https://www.encodeproject.org/search/?type=Experiment&lab.title=Bing+Ren%2C+UCSD&assay_title=ATAC-seq&organ_slims=brain).

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