Supplementary Figure 11: CSF1R inhibition kills brain microglia instead of inducing microglial dedifferentiation. | Nature Neuroscience

Supplementary Figure 11: CSF1R inhibition kills brain microglia instead of inducing microglial dedifferentiation.

From: Repopulated microglia are solely derived from the proliferation of residual microglia after acute depletion

Supplementary Figure 11: CSF1R inhibition kills brain microglia instead of inducing microglial dedifferentiation.

The number of tdTomato-positive cells in microglia-labeled Cx3cr1-CreER::Ai14 mice is significantly reduced after PLX5622 administration for 10 days. All surviving tdTomato-positive cells are co-labeled with Iba1. Green: Iba1; red: tdTomato; blue: DAPI. The experiment has been independently repeated 3 times with similar results.

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