Supplementary Figure 6: Different firing correlations between GAERS TC and NRT neuron pairs. | Nature Neuroscience

Supplementary Figure 6: Different firing correlations between GAERS TC and NRT neuron pairs.

From: Cortical drive and thalamic feed-forward inhibition control thalamic output synchrony during absence seizures

Supplementary Figure 6

(a) Examples of ictal total firing XCors of a TC-WA NRT neuron pair with a symmetric peak centered on the SWC spike (left), a TC-WA NRT neuron pair with no peak or trough (middle), and a TC-WQ NRT neuron pair (right) from GAERS. Orange lines indicate confidence intervals of expected correlations (CI: 5%–95%) estimated from surrogate firing time for each neuron in its respective firing distribution relative to the SWC (Online Methods). Top left insets in (a,f,g) show superimposed autocorrelograms for the respective TC (blue) and NRT (green) neurons calculated between −400 and +400 ms (each curve maximum amplitude is normalized to 1). Top right insets in (a) show superimposed spike distribution of the respective TC (blue) and NRT (green) neuron calculated for the time period −40 to +40 ms with respect to the SWC spike. (b-g) XCors of the same pairs as in (a) for different types of firing (as indicated) during ASs (b-e), awake interictal periods (f) and non-REM sleep (g).

Back to article page