Supplementary Figure 7: Schematic diagram of cerebellar contributions to control of a saccade following experience of an error.
From: Encoding of error and learning to correct that error by the Purkinje cells of the cerebellum
Following a saccade to the right, the target is moved inward, resulting in an error. This single error (vector pointing leftwards), results in changes on two sides of the oculomotor vermis. For the P-cells on the right side, this error is CS-on, producing a reduction in simple spikes. For the P-cells on the left side, the same error is in direction CS-on+180, producing a small increase in simple spikes. The two sides of the cerebellum project to different deep cerebellar nuclei, but their combined effect is a synergistic reduction in the gain of the saccade: reducing the activity of the agonist and increasing the activity of the antagonist muscles. Black filled circles represent inhibitory neurons and white filled circles represent excitatory neurons.
