Supplementary Figure 5: Heterochromatin decondensation increases levels of transposable element transcripts in Drosophila heads. | Nature Neuroscience

Supplementary Figure 5: Heterochromatin decondensation increases levels of transposable element transcripts in Drosophila heads.

From: Pathogenic tau-induced piRNA depletion promotes neuronal death through transposable element dysregulation in neurodegenerative tauopathies

Supplementary Figure 5

NanoString analysis of transposable element transcript levels in Drosophila harboring a loss of function mutation in Su(var)205 shown in a, or Su(var)3-9 shown in b (unpaired, two-tailed Student’s t-test, *P<0.05, **P<0.01, ***P<0.001, n = 6 biologically independent replicates each consisting of RNA pooled from 6 heads, values are relative to control, which was set to 1). Values are mean ± s.e.m. All flies are 10 days old. Full genotypes are listed in Supplementary Table 1. Transposable elements recognized by “generic” probes are listed in Supplementary Table 4

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