Supplementary Figure 8: Temporal profiles of the variance derived from intracranial recordings in 12 patients implanted with seizure prediction devices. | Nature Neuroscience

Supplementary Figure 8: Temporal profiles of the variance derived from intracranial recordings in 12 patients implanted with seizure prediction devices.

From: Loss of neuronal network resilience precedes seizures and determines the ictogenic nature of interictal synaptic perturbations

Supplementary Figure 8

The temporal evolution of signal variance three hours before a seizure, is shown. The dashed line marks 30 minutes before the seizure during which the variance was analyzed. In two patients significant pre-seizure increases in variance were observed. In five patients, the variance significantly decreased. N denotes the number of recorded seizures in each patient. P marks the value of Wilcoxon sign-rank test. The sign after the p-value indicates whether right-tailed (+) or left-tailed (–) Wilcoxon sign-rank test was significant. Lines and shaded lines represent mean and s.e.m. respectively.

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