Supplementary Figure 8: Null model for seven different subproteomes between microglia and EX or IN neurons. | Nature Neuroscience

Supplementary Figure 8: Null model for seven different subproteomes between microglia and EX or IN neurons.

From: A tau homeostasis signature is linked with the cellular and regional vulnerability of excitatory neurons to tau pathology

Supplementary Figure 8

The statistical significance of the results is studied by creating a null model for each subproteome under scrutiny (see Supplementary Figure 4). (a, c, e, g) Null models for MG (microglia) vs EX (excitatory) neurons; (b, d, f, h) Null models for MG (microglia) vs IN (inhibitory) neurons. (a, b) tau; (c, d) promoters; (e, f) tangles; (g, h) protectors. A p-value is computed as the probability to have a value more extreme than the observed one (one-tailed). Sample sizes are the same as Supplementary Figure 4.

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