Supplementary Figure 1: Tau pathology co-localizes with EX, but not with IN neurons in secondary affected regions in EC-tau mice. | Nature Neuroscience

Supplementary Figure 1: Tau pathology co-localizes with EX, but not with IN neurons in secondary affected regions in EC-tau mice.

From: A tau homeostasis signature is linked with the cellular and regional vulnerability of excitatory neurons to tau pathology

Supplementary Figure 1

(a-d) Representative images of MC1+ tau staining co-localized with TBR1+ and SATB2+ EX neurons, but not PVALB+, SST+ or CALB2+ IN neurons, in the PRH (a) and NC (b) of EC-tau mice at 22 months (n = 6 animals, 2 sections each animal), and in the PRH (c) and NC (d) of EC-tau mice at 30+ months (n = 5-6 animals, 2 sections each animal). Scale bar, 20 µm.

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