Supplementary Figure 1: Alternative reactivation metrics.

(a, b) From Fig. 1. Extinction and alternative context exposure decreased the (a) percentage of Arc⁺ cells among eYFP⁺ cells and (b) percentage of eYFP⁺ cells among Arc⁺ cells compared to fear retrieval. No Ext: n = 8 mice; Ext: n = 8 mice; Alt Ctx: n = 6 mice. (c, d) From Fig. 2. During an extinction retrieval test, Ext-Tag mice displayed a (c) trend towards a greater percentage of Arc⁺ cells among eYFP⁺ cells and (d) a greater percentage of eYFP⁺ cells among Arc⁺ cells compared to Acq-Tag mice. The pattern reversed during the spontaneous recovery test. Acq-Tag/ExtTest: n = 8 mice; Ext-Tag/ExtTest: n = 8 mice; Acq-Tag/SpontRec: n = 8 mice; Ext-Tag/SpontRec: n = 7 mice. Data are means ± s.e.m. See Supplementary Table 1 for statistics. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001.