Supplementary Figure 8: SnoRNA target genes and their splicing changes. | Nature Neuroscience

Supplementary Figure 8: SnoRNA target genes and their splicing changes.

From: Profiling allele-specific gene expression in brains from individuals with autism spectrum disorder reveals preferential minor allele usage

Supplementary Figure 8

(a) The exon numbers between splice junctions and snoRNA targeting sites of 29 splicing changing target genes in ASD (n=62). The comparison between the snoRNA and random target data showed significant difference (one-tailed KS test p-value=0.0029). (b) and (c) The correlation between snoRNA expression and splicing changes of their target genes, ASTN2 (b) and SYNE1 (b), in cortex samples (n=62). PSI(%) is the splicing changing data from qPCR data of the previous study4. (d) The correlation of splicing changes between ASTN2 and SYNE1 in cortex samples (n=62).

Back to article page