Supplementary Figure 6: Peer method performance on growing and moving propagation types. | Nature Neuroscience

Supplementary Figure 6: Peer method performance on growing and moving propagation types.

From: Accurate quantification of astrocyte and neurotransmitter fluorescence dynamics for single-cell and population-level physiology

Supplementary Figure 6

Schematic (top) and results (bottom) of performance of five image-analysis methods (AQuA, GECI-quant, CaSCaDe, CaImAn, and Suite2P) on simulated datasets with (a) growing propagation and (b) moving propagation. Change of the propagation frame number is shown in the bottom left panel, and varying SNR in the bottom right, with center point indicating mean. The bars on each curve indicate the 95% confidence interval calculated from 10 independent replications of simulation, where each simulation contains hundreds of events. When the number of propagation frames (not the event duration) is 0, the simulation is under pure ROI assumptions. IoU (intersection over union) measures the overlap between detected and ground-truth events. An IoU of 1 is the best performance achievable by any method, meaning that all detected events are ground-truth and all ground-truth events are detected.

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