Extended Data Fig. 10: CITE-Seq analysis reveals the persistence of cDC1 or cDC2-related proteins in a fraction of MigDCs in human and mouse GBM. | Nature Neuroscience

Extended Data Fig. 10: CITE-Seq analysis reveals the persistence of cDC1 or cDC2-related proteins in a fraction of MigDCs in human and mouse GBM.

From: Single-cell profiling of myeloid cells in glioblastoma across species and disease stage reveals macrophage competition and specialization

Extended Data Fig. 10: CITE-Seq analysis reveals the persistence of cDC1 or cDC2-related proteins in a fraction of MigDCs in human and mouse GBM.The alternative text for this image may have been generated using AI.

a, Protein-based UMAP plot of human DCs, in which MigDCs are highlighted in purple (left). The rectangle delineates the insets shown in the right panels, where the expression of cDC1- or cDC2-related marker genes and their corresponding cell surface proteins are plotted. b, RNA-based UMAP plot of mouse DCs, in which MigDCs are highlighted in purple (left). The rectangle delineates the insets shown in the right panels, where the expression of cDC1- or cDC2-related marker genes and their corresponding cell surface proteins are plotted. c, RNA-based UMAP plots of mouse DCs showing the expression level of H2-Aa in the top panel and the corresponding protein IA-IE in the bottom panel. d, RNA-based UMAP plots of mouse DCs showing showing the expression of the indicated genes and their corresponding cell surface protein markers.

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