Extended Data Fig. 3: Endoneurial snMacs express higher levels of immediate early response genes. | Nature Neuroscience

Extended Data Fig. 3: Endoneurial snMacs express higher levels of immediate early response genes.

From: Profiling peripheral nerve macrophages reveals two macrophage subsets with distinct localization, transcriptome and response to injury

Extended Data Fig. 3: Endoneurial snMacs express higher levels of immediate early response genes.

a, Single-cell heatmap of the immediate early response genes induced by tissues digestions identified by Van Hove et al. and projected on the tSNE populations identified by sc-RNA-sequencing as Relmα+Mgl1+ snMacs and Relmα-Mgl1- snMacs. The heatmap shows the scaled log2 normalised expression values. The log2 normalised expression values were scaled using the ‘scale_quantile’ function of the SCORPIUS package with default parameters (v1.0). b, tSNE plot depicting the expression of canonical immediate early response genes on Relmα+Mgl1+ snMacs and Relmα-Mgl1- snMacs.

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