Extended Data Fig. 2: Activity-induced loops are not present earlier in cortical neuron differentiation. | Nature Neuroscience

Extended Data Fig. 2: Activity-induced loops are not present earlier in cortical neuron differentiation.

From: Three-dimensional genome restructuring across timescales of activity-induced neuronal gene expression

Extended Data Fig. 2: Activity-induced loops are not present earlier in cortical neuron differentiation.

a, Zoom-in heatmaps of critical loops presented throughout the paper. From left to right the columns are Obs/Exp heatmaps of HiC (Bonev et al.) data from 1) embryonic stem (ES) cells, 2) neural progenitor cells (NPC), 3) cortical neurons (CN), followed by 5C interaction score heatmaps across the 4) TTX, 5) untreated, and 6) BIC treated conditions. Genes of interest in each zoom window, Figure panels where same loop is further analyzed, and loop classification are listed on left.

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