Extended Data Fig. 7: Schematic of PCs affected by CS inputs. | Nature Neuroscience

Extended Data Fig. 7: Schematic of PCs affected by CS inputs.

From: Climbing fiber synapses rapidly and transiently inhibit neighboring Purkinje cells via ephaptic coupling

Extended Data Fig. 7

Model showing how PCs are affected by a single inferior olive neuron. Climbing fibers typically have 7 different branches and each contacts a single PC. Based on PC packing density55,56,57, a hexagonal packing pattern, each individual branch will ephaptically inhibit about 18 neighboring PCs while directly exciting 7 PCs.

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