Extended Data Fig. 7: Quantification of TH immunoreactivity.
From: Divergent pallidal pathways underlying distinct Parkinsonian behavioral deficits
a, Representative image of TH immunoreactivity in the striatum of a mouse injected with vehicle (0.02% sodium ascorbate in 0.9% saline). b, Representative image of TH immunoreactivity in the striatum 3 days after bilateral injection of low-dose 6-OHDA (1.25 μg/μl). c, Representative image of TH immunoreactivity in the striatum 10 days after bilateral injection of high-dose 6-OHDA (2.5 μg/μl). d, Quantification of TH immunoreactivity at different stages of dopamine depletion in rescue experiments for reversal learning and locomotion. Data presented as % mean ± SEM of naïve control striatal sections (n = 6 mice for PVGPe-PF: eGFP (vehicle), n = 7 mice for PVGPe-PF: eGFP (OHDA), n = 7 mice for PVGPe-PF: hM4D (OHDA), n = 10 mice for PVGPe-SNr: eGFP (OHDA), and n = 11 mice for PVGPe-SNr: oChIEF (OHDA)). Scale bar, 1 mm (a-c).
