Extended Data Fig. 1: Molecular identity of PVGPe-SNr and PVGPe-PF neurons. | Nature Neuroscience

Extended Data Fig. 1: Molecular identity of PVGPe-SNr and PVGPe-PF neurons.

From: Divergent pallidal pathways underlying distinct Parkinsonian behavioral deficits

Extended Data Fig. 1

a. mFISH experiments for PVGPe-SNr neurons (top row) and PVGPe-PF neurons (bottom row) with several molecular markers for GPe neurons including parvalbumin (Pvalb), somatostatin (Sst), sodium voltage-gated channel beta subunit 4 (Scn4b), LIM homeobox protein (Lhx6), NK2 homeobox 1 (Nkx2-1) and Forkhead box protein P2 (Foxp2). PVGPe-SNr and PVGPe-PF neurons are labelled by the probe against eGFP. Scale bar in a, 20 mm. b, c, Quantification of GFP-labelled PVGPe-SNr neurons (b, n = 3 mice) and GFP-labelled PVGPe-PF neurons (c, n = 4 mice) expressing specific molecular markers. Fractions show the number of neurons expressing each molecular marker out of total GFP positive neurons in sections.

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