Extended Data Fig. 2: WT and 16p11.2+/− mice showed similar performance on the head-fixed rotating-disk task in session 1. | Nature Neuroscience

Extended Data Fig. 2: WT and 16p11.2+/− mice showed similar performance on the head-fixed rotating-disk task in session 1.

From: Delayed motor learning in a 16p11.2 deletion mouse model of autism is rescued by locus coeruleus activation

Extended Data Fig. 2: WT and 16p11.2+/− mice showed similar performance on the head-fixed rotating-disk task in session 1.

a, Schematic of the rotating-disk task. b-c, Mean running attempts (b), distance travelled (c) in session 1. Both groups showed a comparable number of running attempts but had low total distance travelled (WT, n = 10 mice; 16p11.2+/−, n = 7 mice). One-tailed bootstrap test. d-e, Mean RE counts (d) and RE duration (e) in session 1. Both groups showed comparable performance in session 1 (WT, n = 10 mice; 16p11.2+/−, n = 7 mice). One-tailed bootstrap test. f, Mean probability distribution of sub-threshold velocities during SEs in session 1 (n = 7 mice per group). Both groups showed a comparable distribution of velocities. Error bars indicate s.e.m.

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