Extended Data Fig. 7: Effect of bilateral SC inactivation and YFP control.
a, Effect of full-trial and sub-trial inactivations of bilateral SC on Pro (green) and Anti (orange) error rate (mean and s.e.m.) compared to YFP controls (gray). Full-trial: n = 662, 615 for Pro and Anti inactivation trials; n = 362, 322 for Pro and Anti control trials. ***P = 4 × 10−4, two-sided permutation test. Task cue: n = 413, 401 for Pro and Anti inactivation trials; n = 290, 271 for Pro and Anti control trials. Delay: n = 562, 527 for Pro and Anti inactivation trials; n = 315, 260 for Pro and Anti control trials. ***P = 4 × 10−4; **P = 0.0012, two-sided permutation tests. Choice: n = 547, 506 for Pro and Anti inactivation trials; n = 319, 261 for Pro and Anti control trials. All paired statistics shown here are computed using a two-sided permutation test, shuffled 5000 times. b, Effect of full-trial and sub-trial inactivations of bilateral SC on response time (RT). For each behavioral session, a median RT on non-stimulated control trials is calculated and subtracted from the RTs on inactivation trials, and these normalized RT changes due to inactivation are plotted here. Each curve is normalized to have a total area of 1. Vertical bars show the median RT changes for correct Pro and Anti trials; s.e.m. across trials for each trial type are indicated by horizontal bars. A shift to the right indicates slowing due to inactivation and a shift to the left indicates speeding.
