Extended Data Fig. 2: Classification of striatal units and statistics of task-aligned FSI activity in DLS and DMS.
From: The basal ganglia control the detailed kinematics of learned motor skills
a, Classification of single units recorded in striatum into putative spiny projection neurons (SPNs, maroon) and fast spiking interneurons (FSIs, blue). (Left) Spike waveform features such as peak-width and peak-to-valley interval, as well as average firing rates were used in combination to classify units as SPNs or FSIs. Grey dots indicate unclassified units (8.5%) that were excluded from further analysis. (Right) Population averaged spike waveforms for putative SPNs (top) and FSIs (bottom). Data presented as the mean ± s.d. across units. All waveforms were rescaled to unit amplitude prior to averaging. b, Average firing rate during the trial-period (P = 3 × 10−3), maximum modulation of Z-scored firing rate during the trial-period (P = 0.01), sparseness index (P = 0.13) and average trial-to-trial correlation of task-aligned spiking (P = 1 × 10−3) in putative FSIs recorded in the DLS (red, n = 171) and DMS (green, n = 138). Bars and error-bars represent mean and s.e.m., respectively, across units. P values measure the two-sided probability that two datasets have the same mean and are computed by bootstrapping difference in the means (n = 1 × 104 resamples).
