Extended Data Fig. 10: Caffeic acid rescues aberrant levels of arachidonic acid in the sMN culture of multiple ALS hiPC lines. | Nature Neuroscience

Extended Data Fig. 10: Caffeic acid rescues aberrant levels of arachidonic acid in the sMN culture of multiple ALS hiPC lines.

From: Multi-omic analysis of selectively vulnerable motor neuron subtypes implicates altered lipid metabolism in ALS

Extended Data Fig. 10

(A-F) Ion count value shows arachidonic acid level is down-regulated in post-treatment with 25 μg/ml CA at D11 to D17 of sMN differentiation of control and CA treated of ALS hiPSC lines (at least n=3 for each group; the cell line names are listed; technical replicates; biological replicates; *P<0.05, **P<0.01, ***P<0.001, two-tailed; unpaired student’s t-test). (G) Schematic model of this study. Error bars: mean ± SEM.

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