Fig. 2: Clone reconstruction across cell types and regions in the mouse telencephalon.
From: Clonal relations in the mouse brain revealed by single-cell and spatial transcriptomics
a–d, UMAP visualizations of all cells isolated from barcoded samples grouped by cell type (a), cloneID-expressing cells (b), number of cloneIDs per cell (c) and cells in multi-cell clones (d). e, Box plots showing average clone sizes (number of cells per clone). The average clone size varies depending on cell type and is 4.9 ± 0.3 cells per clone (mean ± s.e.m., n = 2,360 clones) when considering all cell types (left), 4 ± 0.1 cells per clone (mean ± s.e.m., n = 2,276 clones) when considering only neuroectoderm-derived cells (middle) and 29.5 ± 7.6 cells per clone (mean ± s.e.m., n = 84 clones) when considering only mesoderm-derived immune cells (right). For each plot, the center line represents the median; the bounds of the box represent the interquartile range; and the whiskers represent the lower and upper limits. Black dots represent outliers, and red dots represent the average clone size. f, Bar plots showing total number of cells in clones for each cell type. g, Dot plots and bar plots displaying the total proportion of cells in clones for each cell type (top) and per region (bottom).
