Extended Data Fig. 8: Synergy-redundancy gradient correlates with unadjusted cortical expansion and gene expression.
From: A synergistic core for human brain evolution and cognition
(a) Significant Spearman correlation (two-sided CI: [0.145, 0.476]) between regional redundancy-to-synergy gradient scores and unadjusted regional cortical expansion from chimpanzee (Pan troglodytes) to human (both on DK-114 cortical atlas, both hemispheres; n =114 cortical regions). (b) Significant Spearman correlation (two-sided CI: [0.109, 0.567]) between regional redundancy-to-synergy gradient scores and unadjusted regional expression of brain-related human-accelerated (HAR) genes (both on left hemisphere of DK-114 atlas: n=57 left-hemisphere regions). (c) Significant Spearman correlation (two-sided CI: [0.010, 0.496]) between regional redundancy-to-synergy gradient scores and unadjusted regional expression of non-brain-related human-accelerated (HAR) genes (both on left hemisphere of DK-114 atlas; n=57 left-hemisphere regions). p_spin indicates the p-value estimated from a spatial permutation test comparing the empirical correlation against 10,000 randomly rotated brain maps with preserved spatial covariance.
