Extended Data Fig. 7: Macaque adult hippocampal transcriptomic cell types are aligned with well-established human datasets.
From: Single-cell transcriptomics of adult macaque hippocampus reveals neural precursor cell populations
a) UMAP visualization of macaque hippocampal transcriptomic cell types aligned with the Li dataset. UMAP visualization of macaque cells (n = 2,400) and human embryonic/fetal cells (n = 323), stained with the species. b) UMAP visualization of macaque cell annotations using the same UMAP coordinates in panel a, stained according to the color scheme as in Fig. 1d. Astro, Astro_1–4; GC, GC_1–3; MG, Microglia_1 and 2; OPC, OPC_1 and 2; Pyr, Pyr_1 and 2; RGL, RGL_1 and 2. c) UMAP visualization of human cell annotations using the same UMAP coordinates in panel a, stained according to the color scheme as in Fig. 1d. d) Macaque hippocampal transcriptomic cell types aligned with the Zhong dataset, visualization of macaque cells (blue, n = 15,878) and human cells (orange, n = 6,383) e) UMAP visualization of macaque cells, stained according to the color scheme in Fig. 1d using the same coordinates as in panel d. f) UMAP visualization of human cells, stained according to the color scheme in Fig. 1d using the same coordinates as in panel d. g) Cell-type homologous heatmap between macaque (in rows) and human (in columns) for the Zhong et al. dataset. The color of each cell represents the alignment score between human and macaque cells. The larger value (darker in the heatmap) indicates a better alignment. Rows show macaque populations and columns show human populations. Colorbar indicates the alignment score.
