Extended Data Fig. 3: FSCV Recordings of the Extracellular 5-HT Dynamics in BA.
From: Distinct serotonergic pathways to the amygdala underlie separate behavioral features of anxiety
(a-d) Representative pseudo colour plots (a), voltammograms (b), traces (c) and statistics (d, n = 9 events from 3 mice; two-sided paired t test; t(8) = 7.512, ****P < 0.0001) of changes of 5-HT under social stimulus, triangles in a represent time point of voltammograms in b (e-g) Representative pseudo colour plots (e) and voltammograms (f), traces (g) and statistics (h, n = 13 events from 3 mice; two-sided paired t test; t(12) = 4.495, ***P = 0.0007) of changes in 5-HT under ~300 Lux stimulus, triangles in e represent time point of voltammograms in f (i) Voltage applied to carbon fiber electrodes during FSCV recording of 5-HT. (j-m) Schematic of virus injection (j, l) and 5-HT cyclic voltammograms (k, m, background subtracted) after opto-stimulation of DRN5-HT neurons.
