Fig. 1: Sounds evoke stereotyped responses in visual cortex.

a, Responses of an example neuron to combinations of sounds (columns) and videos (rows). Responses were averaged over four repeats. b, Video-related time courses (averaged over all sound conditions, minus the grand average) for the example neuron in a. c, Same, for the sound-related time courses. d, Grand average over all conditions for the neuron. Scale bars in b–d: 20 spikes per second. e, Sound-related time courses for all 212 neurons in one experiment, sorted using rastermap¹³. f, Decoding accuracy for video versus sound (double asterisks indicate P = 0.0039, Wilcoxon right-tailed signed rank test, n = 8 mice). Dashed lines show chance level (1/12). g, Time courses of the first principal component of the sound-related responses in e (‘auditory PC1’, arbitrary units). h, Fraction of total variance explained by auditory PCs, for this example mouse; inset: distribution of the weights of auditory PC1 (arbitrary units), showing that weights were typically positive. i, Same, for visual PCs. j–l, Same as g–i, for individual mice (thin curves) and averaged across mice (thick curves).