Extended Data Fig. 3: Immunofluorescence mapping of expression of KCC2 in the varying brain regions in MRS. | Nature Neuroscience

Extended Data Fig. 3: Immunofluorescence mapping of expression of KCC2 in the varying brain regions in MRS.

From: Emergence of consciousness from anesthesia through ubiquitin degradation of KCC2 in the ventral posteromedial nucleus of the thalamus

Extended Data Fig. 3

(a–e) Immunofluorescence of KCC2 expression in the thalamus, hypothalamus, cortex, and hippocampus (a) and in the seven sub-nuclei of the thalamus and hypothalamus including MHb, LHb, paraventricular thalamic nucleus (PV)(b), and the VPM (c), and sub-nuclei of the hypothalamus including lateral hypothalamic area (LH), substantia innominate (SI)(d), and paraventricular hypothalamic nucleus (PVN)(e). (f) Data analysis and summary. Mean ± s.e.m., n = 4 mice in each group. One-way ANOVA with Dunnett’s multiple comparisons. P > 0.9999 (NA versus Pro, cortex), P = 0.309 (NA versus Pen, cortex), P = 0.9946 (NA versus Pro, hippocampus). NS = not significant. ****P < 0.0001 in all the others comparisons as indicated. Detailed statistics information is provided in Supplementary Table 1.

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