Extended Data Fig. 6: Correlation analysis of curve slope of entering MRS, duration of MRS, and curve slope of exiting from MRS during LORR, related to Fig. 1.
(a) Diagram illustrating the three parameters of curve slope of entering MRS, duration of MRS, and exiting from MRS during LORR. These three curves were firstly fitted linearly and then analyzed for their correlations. (b) Correlation analysis showing no correlation between any two of the three parameters of curve slope of entering MRS, duration of MRS, and exiting from MRS, related to Fig.1b. n = 5 mice. (c–e) Knockdown of KCC2 in VPM did not affect the correlation between any two of the three parameters, related to Fig. 2c, e, g. Number of mice (c-e): n = 6 in each group of miRNAi (NC); n = 7, 6, and 7 in each group of miRNAi(KCC2). Linear regression analysis was performed for any two of the three parameters, and the correlation between the two parameters was analyzed by nonparametric Spearman correlation analysis. P-values (two-tailed) are indicated on each graph, and less than 0.05 was defined as a significant difference. Detailed statistics information is provided in Supplementary Table 1.
