Extended Data Fig. 10: Prefrontal mechanistic basis of chronic pain-fear interaction.
From: Prefrontal engrams of long-term fear memory perpetuate pain perception
Model based on results of this study to explain the cellular basis of how long-term fear memory induced by a painful episode can alter the perception of tonic pain as well as nociceptive hypersensitivity in chronic neuropathic or inflammatory pain conditions at a remote point in life.
