Table 1 ASD omic datasets included in this study. All sequencing datasets were retrieved from the SRA
Organism | Body type | Data type | Number of studies | Number of subject pairs | References |
|---|---|---|---|---|---|
Human | Postmortem brain tissue | RNAseq | 4 | 49 | Velmeshev et al. 2019 (ref. 59); Wright et al. 2017 (ref. 60); Herrero et al. 2020 (ref. 61); SRP072713 (ref. 62) |
Human | Serum | Immune markers | 1 | 22 | Zurita et al. 2020 (ref. 24) |
Human | Serum | Metabolome | 2 | 50 | Needham et al. 2021 (ref. 49); Kuwabara et al. 2013 (ref. 48) |
Human | Urine | Metabolome | 1 | 26 | Noto et al. 2014 (ref. 50) |
Human | NA | Dietary survey | 1 | 26 | Berding & Donovan 2019 (ref. 25) |
Human | NA | Behavioral survey | 1 | 28 | Kang et al. 2019 (ref. 52) |
Microbial | Fecal | Metabolome | 2 | 43 | |
Microbial | Fecal | 16S amplicon | 10 | 346 | Berding & Donovan 2019 (ref. 25); Zurita et al. 2020 (ref. 24); Dan et al. 2020 (ref. 28); Chen et al. 2020 (ref. 22); Fouquier et al. 2021 (ref. 23); Zou et al. 2020 (ref. 27); Kang et al. 2019 (ref. 52) and 2017 (ref. 26); Son et al. 2015 (ref. 36); David et al. 2021 (ref. 37); SRP299486 (ref. 29); Martin-Brevet et al.38 |
Microbial | Fecal | Shotgun metagenomics | 3 | 83 | Averina et al. 2020 (ref. 34); Wang et al. 2019 (ref. 33); Dan et al. 2020 (ref. 28) |