Extended Data Fig. 4: Discrimination performance in both task variants was qualitatively similar before and after TED implantation.
From: Using temperature to analyze the neural basis of a time-based decision
(a) Discrimination performance of rats trained on the no-fixation variant of the interval discrimination task and implanted with the initial version of our custom TED targeting the DS (N = 4) on the last day of training before surgery. Gray lines are psychometric fits to individual animals. The black line is a fit to the average across animals. The underlying choice data is shown for the cohort average (± s.e.m.). (b) Same as (A), but for rats that trained on the fixation task variant and implanted with the initial (N = 1) or final version of our custom TED targeting the DS (N = 6). (c) Same as (B), but for rats implanted with the final version of our custom TED targeting M1 (N = 4). (d) Schematized timeline for a typical experimental rat. Elongated bars illustrate long periods of time, whereas squares represent individual daily sessions, which, with the exception of surgeries, lasted for 2 hours. (e-g) Same as (A-C), but for the last post-surgery training session in advance of starting temperature manipulation sessions.
