Extended Data Fig. 9: Changes in gliotransmitters after astrocyte inhibition and their effects on mouse behaviors. | Nature Neuroscience

Extended Data Fig. 9: Changes in gliotransmitters after astrocyte inhibition and their effects on mouse behaviors.

From: Cortical astrocytes modulate dominance behavior in male mice by regulating synaptic excitatory and inhibitory balance

Extended Data Fig. 9: Changes in gliotransmitters after astrocyte inhibition and their effects on mouse behaviors.

(a) Glutamate and ATP assays from acute mPFC tissues (n = 8 in each group) and by in vivo microdialysis (n = 8 in each group). Two-tailed Wilcoxon rank-sum test. (b) Mouse locomotion, anxiety and depressive-like behaviors upon Opto-vTrap injection in dmPFC with blue light stimulation during whole experimental sessions (1 Hz, 0.5 sec duration) (n = 8 in each group). Two-tailed Wilcoxon rank-sum test. Scale bar, 500 μm. n.s.: not significant. Data are presented as mean ± s.e.m.

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