Fig. 5: Purkinje cells in conjunction regions are required for maintaining preparatory activity. | Nature Neuroscience

Fig. 5: Purkinje cells in conjunction regions are required for maintaining preparatory activity.

From: Activity map of a cortico-cerebellar loop underlying motor planning

Fig. 5

a, Electrophysiology recording and optogenetic perturbations in L7-cre mice crossed with Ai32 during behavior. b, Spike rates of three example neurons in control trials (left) and in photostimulation trials (right). Blue indicates ‘lick right’ trials; red indicates ‘lick left’ trials. Dashed lines mark behavioral epochs. c, Population selectivity (mean ± s.e.m. across neurons) in conjunction regions. Selectivity is the difference in spike rate between the preferred and non-preferred trial types during the delay epoch. Left, control; right, photostimulation trials. All neurons with significant selectivity during the delay epoch and that were tested for >3 trials in all conditions were included (n = 88). The dashed line represents the mean from control trials.

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