Fig. 5: Cell–cell proximity across all neuronal cell types.
a, Enrichment of cell–cell proximity of different subtypes shown in dot plot (total number of neurons = 32,811). The left half of each dot indicates the cell–cell proximity in PFC and the right half dot indicates that outside the PFC. The color represents log2-transformed observation to expectation of colocalized frequency of the two clusters. The size of dots indicates the significance of the colocalization (a′ shows an enlarged inset highlighting examples of proximities that are different ‘in’ and ‘outside’ of PFC). b, A representative slice showing the cell locations of Pvalb 1 and L5 IT 3 neurons (left), and Pvalb 6 and L5 ET 2 neurons (right). c, A representative slice showing the cell locations of L2/3 IT 3 and L4/5 IT 2 neurons. The dotted lines mark the PFC region.
