Extended Data Fig. 3: Individual subject fits in optogenetics experiments.

Note: the posterior density plots (right panels) show posteriors for control and silencing data, but the samples are in fact paired. Thus, the overlap of the distributions does not reflect the statistical estimate of the shift. See Supplementary Tables 1 and 2 for the confidence intervals of the parameter shifts. a. Left: Subjects’ choices superimposed with the inactivation model fit on control (in gray) and bilateral FOF inactivation (in purple) dataset simultaneously. The circles with error bars are the binned mean and 95% binomial confidence intervals. The ribbons are model predictions generated using the fitted parameters. The solid line represents the model-predicted probability of lottery choice, the dark and light shade represent 50%, 80% confidence intervals, respectively. Right: Posterior distributions of transformed model parameters for each subject in the bilateral FOF optogenetic experiments (n = 3,058 trials, 5 rats). b. as in a but for the unilateral optogenetic silencing of FOF (n = 13,080 trials, 8 rats).