Extended Data Fig. 6: Place preference for animals with one optical fiber implanted correctly.

a. Attempted bilateral implants often resulted in one optical fiber implanted in a target region, and another implanted completely elsewhere devoid of halorhodopsin expression. We examined these mice’s behavior in the place preference protocol as in Fig. 3. b. Example (left) and average (right) position heatmaps for corresponding days of the place preference protocol for mice with unilateral implants in the PBN (b, n = 5). c. As in (b), but for unilateral implants in the DCN (c, n = 3). d. Implant locations for all mice with color indicating bottom chamber preference (Test/Baseline; D2/D1). e. Summary of the % time spent in the bottom chamber across all test days for PBN (red) and DCN (blue) unilaterally implanted PCP2-cre/Halo mice. (see Supplementary Table 3).