Extended Data Fig. 9: VTADA neuron excitation leads to a better performance in anxiety-like behaviors at the early stage after SNI surgery.
a, Schematic of the injection of Cre-dependent chemogenetic activation virus (GFP) into the VTA of TH-Cre mice, followed by the SNI surgery. b, Statistics of OFT behavior of chemogenetic activation (n = 7) and control (n = 7) groups 7 days after the SNI surgery. c, d, As in (a, b), except that CaMKII-Cre virus and Cre-dependent optical inhibitory virus were co-injected into the ACC and C57 mice were used (Control, n = 7; NpHR, n = 7). The data are presented as the mean ± s.e.m. Unpaired Student’s t-test, *P < 0.05, **P < 0.01. Detailed statistics information can be found in the Source Data.
