Extended Data Fig. 5: Automated clustering of spatial sequencing. | Nature Neuroscience

Extended Data Fig. 5: Automated clustering of spatial sequencing.

From: Proteomic and transcriptomic profiling of brainstem, cerebellum and olfactory tissues in early- and late-phase COVID-19

Extended Data Fig. 5

Heat map of the top 5 most expressed genes per cluster of integrated spatial sequencing data from all sequenced samples. The color represents normalized and scaled (‘SCTtransform’, Seurat) gene expression (a). These unsupervised clusters are distributed similar to the supervised anatomical annotation shown in Fig. 3 with clusters of brainstem nuclei and white matter fiber tracts (b; left panel: acute (patient D10), right panel: late (patient D19)).

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