Extended Data Fig. 7: T cell comparison in lung, olfactory mucosa and brain (snRNA Seq). | Nature Neuroscience

Extended Data Fig. 7: T cell comparison in lung, olfactory mucosa and brain (snRNA Seq).

From: Proteomic and transcriptomic profiling of brainstem, cerebellum and olfactory tissues in early- and late-phase COVID-19

Extended Data Fig. 7

Integrated UMAPs of natural killer cells (NK), CD4+ and CD8 + T cells within the brainstem, olfactory mucosa and lung in acute and late COVID-19 and controls in the single-cell RNA-seq datasets (a). The Venn diagram represents all unique and shared T cell related transcripts in the brainstem, olfactory mucosa and lung (b). Dot plot of snRNA sequencing activation (c) and cytotoxic markers (d) in CD8 + T cells in the brainstem. Expression levels are color coded; the percentage of cells expressing the respective gene is size coded (c, d). Integrated heatmap of cytotoxic and activation markers in T cells of lung, brainstem and mucosa (e).

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