Extended Data Fig. 5: Fast inhibitory plasticity or weak inhibitory control over excitatory plasticity prevents the stable formation of receptive fields. | Nature Neuroscience

Extended Data Fig. 5: Fast inhibitory plasticity or weak inhibitory control over excitatory plasticity prevents the stable formation of receptive fields.

From: Co-dependent excitatory and inhibitory plasticity accounts for quick, stable and long-lasting memories in biological networks

Extended Data Fig. 5

a and b, Same simulation protocol used in Fig. 5a,b, but with larger learning rate of inhibitory plasticity (increased by 50-fold). Evolution of excitatory (top) and inhibitory (bottom) weights. The shaded area (*) indicates the learning window, when all inhibitory afferents are down-regulated. Excitatory input groups are activated for receptive-field formation during the learning window (Extended Data Fig. 4). c, Snapshots of the average synaptic weights for the different pathways at the moments indicated by the ⋆ symbols in panels a and b. d and e, Same as panels a and b, but with weak inhibitory control over excitatory plasticity rather than fast inhibitory plasticity. f, Snapshots of the average synaptic weights for the different pathways at the moments indicated by the ⋆ symbols in panels d and e.

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