Extended Data Fig. 1: Contribution of spike times, excitation, and inhibition to weight changes for the codependent synaptic plasticity model.

a-c, Schematics of the sequence of spikes (left), and the resulting weight change for two different spike patterns (middle and left) for codependent excitatory synaptic plasticity model as a function of the levels of excitation and inhibition during plasticity. a, Spike triplet: post-pre-post sequence with fixed pre-before-post spike interval, ΔtLTD, and two examples for intervals between two consecutive postsynaptic spikes, Δthet. b, Doublet: post-before-pre spike pattern with two different intervals, ΔtLTD. c, Postsynaptic burst with two spikes at different interspike intervals, Δthet. d, Same as panel b for codependent inhibitory synaptic plasticity model.