Extended Data Fig. 7: Factor increase in dopamine effects on neuron firing rates.
From: Constraints on the subsecond modulation of striatal dynamics by physiological dopamine signaling
a. Changes in MSN firing rates compared to baseline as a function of factor increase in dopamine. n = 26 sessions from 9 Chrimson-expressing mice, and n = 12 sessions from 4 control mice. Chrimson group MSN data are positively correlated with the factor increase in dopamine (Pearson r = 0.6, P = 0.0033). Dashed line represents the highest value seen in the control data. Blue line represents the linear fit to the Chrimson data. b. Changes in FSI firing rates compared to baseline as a function of factor increase in dopamine (Pearson r = 0.005, P = 0.98). Dashed line represents the highest value seen in the control data. c. Changes in TAN firing rates compared to baseline as a function of factor increase in dopamine (Pearson r = 0.12, P = 0.55). Dashed line represents the highest value seen in the control data.
