Extended Data Fig. 5: Diversity of single-cell response profiles.
From: Population-level coding of avoidance learning in medial prefrontal cortex
(a) Trial-averaged and z-scored neural activity (Methods) of all recorded cells during avoid trials of an example session (session 7). Activity is aligned to tone start (left) or shuttle start (right), as shown, for example, cells, in Fig. 1l. Cells are sorted according to their time-averaged z score in the 3 s window after tone start (window is indicated by the black bar at top of panel). This sorting reveals that cells tend to have different responses in the tone start and shuttle start windows. Barcode indicates if cells were classified as trial-responsive (black) or not (white). (b) Same as a, but cells are sorted according to their mean z score in the 3 s window preceding shuttle start. This sorting reveals that the activity preceding shuttle actions tends to be different from both the activity at tone start and the activity after shuttle start. (c) Same as a, but cells are sorted according to their mean z score in the 1 s window after shuttle start. Overall, responses are highly diverse over the population because cells show different combinations of activity levels for the different task-related events.
