Fig. 1: Brainstem–cortex FC.
From: Integrating brainstem and cortical functional architectures
a, Coronal (posterior view), saggital and axial view of the thresholded (35%) probabilistic template for all 58 brainstem nuclei in the Brainstem Navigator atlas (https://www.nitrc.org/projects/brainstemnavig/ (ref. 15)). b, Coronal (posterior view), saggital and axial view of cortical (gray points, n = 400) and brainstem (green points, n = 58) parcel coordinate centroids. c, Left, FC matrix (458 regions × 458 regions). Right, FC matrix between cortex and brainstem (400 cortical regions × 58 brainstem nuclei). d, Density distributions of FC within brainstem (green), between brainstem and cortex (blue) and within cortex (pink). e, Scatter plot of FC between regions as a function of Euclidean distance between parcel centroids. Within-cortex two-sided Spearman’s r = −0.29, P ≈ 0; brainstem–cortex two-sided Spearman’s r = 0.05, P = 8.7 × 10−16; within-brainstem two-sided Spearman’s r = −0.11, P = 3.4 × 10−6.
