Fig. 7: Protein-connectivity associations. | Nature Neuroscience

Fig. 7: Protein-connectivity associations.

From: Integration across biophysical scales identifies molecular and cellular correlates of person-to-person variability in human brain connectivity

Fig. 7

a, Histogram on the number of associations found between proteins or their dendritic spine component and functional connectivity, aggregated over regions and effects tested. Red dotted line corresponds to the FDR threshold for the dendritic spine component. b, GO term enrichment based on applying GSEA to protein-connectivity association statistics. Displayed scatterplot corresponds to interaction effects. Ranking of GO terms is similar between SFG and ITG. c, Structural covariation counterpart of a. d, Structural covariation counterpart of b. e, Sankey diagram displaying enriched GO terms common between functional connectivity (FC) and structural covariation (SC) as outcome, and proteins associated with both FC and SC (in terms of main effect, interaction or joint of main and interaction effect) that overlap with members of the GO terms.

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