Extended Data Fig. 4: Quality control of ST data and histopathological lesion assessment.
From: Cell type mapping reveals tissue niches and interactions in subcortical multiple sclerosis lesions
a, Distribution of number of genes per spot (left), distribution of number of UMIs per spot (center) and total number of spots per ST sample (n per sample is represented at the right). b, ST feature plots showing H&E staining, number of UMIs per spot, number of expressed genes per spot and annotated histopathological areas for each analyzed sample. c, IHC for LFB (left) to visualize demyelinated lesion areas in MS samples and IHC for CD163 (right) to highlight inflamed lesion areas of analyzed samples. Overview scale bar 500µm.
