Fig. 1: Postmortem data and immunohistochemistry photomicrographs. | Nature Neuroscience

Fig. 1: Postmortem data and immunohistochemistry photomicrographs.

From: Sympathetic and parasympathetic subtypes of body-first Lewy body disease observed in postmortem tissue from prediagnostic individuals

Fig. 1: Postmortem data and immunohistochemistry photomicrographs.

a, A total of 16 anatomical regions staged for Lewy pathology in 173 BBAR cases. b, A plot depicting the eight dissemination categories on the x axis and the percentage of diagnosed PD or DLB cases on the y axis. As diagnosed PD and DLB cases were primarily seen in the two final categories, the first six categories were defined as prediagnostic and the two most disseminated categories were postdiagnostic. c, Representative photomicrographs showing phosphorylated α-synuclein immunohistochemical staining in cortical, limbic, brainstem and peripheral tissues. Scale bars, OB 500 µm (insert 50 µm); AMY, DMV and SY 100 µm; all others 25 µm.

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