Extended Data Fig. 8: HTR2C receptor is not necessary for baseline rates of ChP apocrine secretion.
From: Choroid plexus apocrine secretion shapes CSF proteome during mouse brain development
(A) Representative SEM of E16.5 Htr2c KO mouse LV ChP 30 min after maternal injection of a vehicle control (left), WAY-161503 (middle), and a C57BL6/J WT mouse after WAY-161503 (right). scale bars 30 µm. (B) Quantification of aposomes. N = 20 mice from 4 litters. (C) Representative confocal images and quantification of epiplexus immune cells after maternal saline (N = 6) or PolyI:C delivery (24H N = 9, 48H N = 5). Scale bar 100 µm. P values from one-way ANOVA. Data Presentation: All data presented as mean ± SEM. P values from Kruskal-Wallis test for (B) and from one-way ANOVA with Tukey correction for (C).
